Cannot start Microsoft Outlook Cannot open the Outlook window

Cannot start Microsoft Outlook Cannot open the Outlook window, but it can get misconfigured and refuse to start. In this article, we’ll discuss one such error. Start Microsoft OutlookIf you keep getting the following message, starting Microsoft Outlook can be quite a task: “Cannot start Microsoft Outlook. Cannot open the Outlook window. The set of folders cannot be opened.”

The cause of this problem in Microsoft Outlook is unknown. However, the primary reason that can be attributed to the appearance of this error is either a corrupt Outlook PST file or corrupt Navigation Pane settings file – myprofile.XML, where ‘myprofile’ is Outlook profile name. You can determine if your Outlook file is probably corrupt if the file in question shows 0 KB size.

Cannot start Microsoft Outlook, Cannot open the Outlook window

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If you receive a strange error, you might try restarting your system and checking if the issue fixes itself. You can also try running Outlook in compatibility mode and see if this helps. If you are already running it in Compatibility Mode, turn it off and see if that resolves the issue. For some users, the issue may resolve itself, while for others, a fix is needed to be applied. Here are the ways, which could help you to get rid of this issue.

Outlook won’t open

1] Start Outlook in Safe Mode

Open Run box, type outlook /safe and hit Enter to open Outlook in Safe Mode.

If Outlook is having trouble opening, then you may need to check your add-ins or extensions for anything that could be blocking it. You can try this in two ways. You can either disable everything and then it on one by one or, you can disable one and relaunch Outlook to check if everything is working fine. If not, you have found the problem.

  • To open the Outlook Options window, click File > Options.
  • Add-ins can be found in the Add-ins section.
  • Click on the Go button next to Manage Comm Ad-ins at the bottom of this section.
  • You can disable add-ons and relaunch Outlook from here.

2] Turn off Compatibility mode in Outlook

If you’re having trouble with Outlook, one possible reason is that it’s running in compatibility mode. Compatibility mode is designed to help programs run on older operating systems. If Outlook is running in compatibility mode, you can turn it off and see if it fixes the problem.

To find the Outlook.exe file on your computer, open the Office software folder. If you are running the latest version of Office, the file will be in the top-level folder.

C:\Program Files\Microsoft Office\root\Office16

or at

C:\Program Files (x86)\Microsoft Office\root\Office16

Right-click the Outlook.exe file and select Properties. In the Compatibility tab, check the Run this program in compatibility mode for: option and select an older version of Windows from the drop-down menu. The Compatibility tab may have some checked boxes. Uncheck them, then select ‘Apply’ > OK. Restart Outlook. The problem should get resolved.

3] Reset the Outlook navigation pane

Press Windows Key + R and type following into the Run box, hit Enter key then:

Outlook.exe /resetnavpane

Outlook will be started when you hit Enter key. This command will clear and regenerate the navigation pane for the current Outlook profile, which should fix the problem. If it does not, try the next fix.

4] Create a new Outlook profile

Open up Control Panel and search for “mail”.

Click on the Mail icon which appears. In the Mail Setup – Outlook window, click Show Profiles.

In the ‘Mail’ window, add your new profile. Then choose ‘Always use this profile’ and select your newly added profile from the drop-down.

Click Apply followed by OK.

Now you can try restarting your Windows computer to see if Outlook will open.

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